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2025 MLB Awards Watch: MVP, Cy Young and more for September

by admin September 10, 2025


  • Bradford DoolittleSep 10, 2025, 07:00 AM ET

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      • MLB writer and analyst for ESPN.com
      • Former NBA writer and analyst for ESPN.com
      • Been with ESPN since 2013

Just as baseball’s postseason chase has entered the stretch run, those vying for individual honors are running out of time to make their cases.

This is our fourth and final Awards Watch of the regular season, and with that in mind, we’ve changed up our usual format to narrow the focus of each race to the leading contenders in each category.

What races are all but decided? Which ones remain very much up in the air? Let’s dig in.

Most Valuable Player

Olivia Vanni/Getty Images

American League

Leading contenders: Aaron Judge, New York Yankees (153 AXE) vs. Cal Raleigh, Seattle Mariners (144)

Next eight: 3. Bobby Witt Jr., Kansas City Royals (142); 4. Jose Ramirez, Cleveland Guardians (135); 5. Julio Rodriguez, Mariners (132); 6. Vladimir Guerrero Jr., Toronto Blue Jays (131); 7. Byron Buxton, Minnesota Twins (130); 8. Corey Seager, Texas Rangers (129); 9. (tie) Jeremy Pena, Houston Astros, Cody Bellinger, Yankees, Maikel Garcia, Royals (128)

ESPN BET top two: Judge (-350, 78% chance of winning), Raleigh (+200)

Sizing up the race: This race is closer than AXE and the odds suggest. In fact, it would not surprise me if they are wrong altogether. Either way, the chase isn’t over.

What is AXE?

AXE is a rating system developed to combine the results from the leading publicly available value metrics to create a consensus evaluation of each player. These include bWAR, fWAR, win probability added and championship probability added. The ratings for each system are combined using standard scores and weighted to best fit the current standings.

The results are expressed as an index, with 100 as average, 110 as one standard deviation above, 120 two standard deviations above, 90 one standard deviation below, etc.

The manager version of AXE (EARL) considers factors that tend to influence postseason balloting in this category, like winning above/below preseason expectation, outperforming run differential, performance in close games, etc. It should not be viewed as a measure of managerial ability.

Odds from ESPN Bet are listed and used as the basis for the implied probability percentages noted with them.

It shouldn’t be controversial to suggest that Judge has had the better offensive season despite Raleigh’s historic home run pace and league-leading RBI total. His percentages are decidedly better across the board, and even if you contextualize for playing venue, Judge has a 40-point edge in OPS+ and, at FanGraphs, a 37-point bulge in wRC+. Raleigh has played in more games, but Judge has still created 31 more runs while using 68 fewer outs. Judge also leads AL hitters in both win probability added and championship probability added. Raleigh ranks fifth in both stats, which are folded into the AXE calculations.

After that, a number of factors tilt toward Raleigh. As a catcher, Raleigh plays a more valuable defensive position and has played it very well. FanGraphs ranks him as the fourth-most valuable defender in the AL. Of course, a chunk of that is due to pitch-framing metrics, which are measured differently at Baseball Reference, which is why Judge has a more commanding lead in that site’s version of WAR.

Then we come to factors of narrative. Raleigh might be having the best season a catcher has ever had. He already has crushed the single-season record for home runs by a backstop and is on the cusp of passing the record for switch-hitters set 64 years ago by Mickey-freaking-Mantle. If that happens, and if Raleigh gets to 60 homers — as a catcher — and does so on a playoff team, how does he not win MVP?

How it can flip: Raleigh has hit .208 since the All-Star break, and as his season average slips downward, soon to drop under .240, you do wonder if he’s vulnerable to an end-of-season crash. He is a catcher after all, and as much as the Mariners try to give him DH days to take the load off, he might be wearing down. If he flails from here and the Mariners miss the playoffs, a typical finish from Judge might be enough to convince voters their heads should never have turned toward Raleigh in the first place.

Prediction: Raleigh breaks Mantle’s record, doesn’t reach 60 homers, but keeps his numbers just strong enough to fend off Judge at the finish line.

National League

Leading contenders: Shohei Ohtani, Los Angeles Dodgers (152 AXE) vs. Juan Soto, New York Mets (140)

Next eight: 3. Trea Turner, Philadelphia Phillies (138); 4. (tie) Pete Crow-Armstrong, Chicago Cubs, Fernando Tatis Jr., San Diego Padres, Geraldo Perdomo, Arizona Diamondbacks (135); 7. (tie) Corbin Carroll, Diamondbacks, Francisco Lindor, Mets (132); 9. Kyle Tucker, Cubs (131); 10. (tie) Will Smith, Dodgers, Ketel Marte, Diamondbacks, Brice Turang, Milwaukee Brewers, Nico Hoerner, Cubs, Kyle Schwarber, Phillies (127)

ESPN BET top two: Ohtani (-25000, 99.6% chance of winning), Schwarber (+2500)

Sizing up the race: Ohtani seems to have a stranglehold on this one, especially since the betting markets favor Schwarber as his leading challenger. Nothing against Schwarber, who is having an epic season, but the metrics don’t support that at all.

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Although the leaderboard happily stretches down to Schwarber’s spot because of ties, you can see that it’s basically Ohtani and everybody else. He combines Schwarber’s power in the slugging and homer categories with virtually all of Soto’s on-base mastery. Soto is having a shockingly prolific season in the steals category, but given that Ohtani has lapped the field in runs scored, he still wins the baserunning part of the race. And, oh yeah, Ohtani tacks on 36 innings of excellent pitching (2.17 FIP), giving him plenty of defensive value as opposed to the negative fielding metrics of both Soto and Schwarber, primarily a DH.

On the contextual side, Ohtani leads the NL in win probability added and championship probability added. Soto is second in both categories, and Schwarber is out of the top 10. Again: Advantage Shohei.

How it can flip: Ohtani appears to have his fourth MVP trophy — and third straight — all but in the bag. Only Barry Bonds (seven) has won more often. And only Bonds, who won each season from 2001 to 2004, has won three seasons in a row. As for the others, of all the names on the leaderboard, Turner has been the hottest of late, so maybe he ends up in the No. 2 slot by season’s end.

Prediction: Ohtani in a landslide.

Cy Young

Brandon Sloter/Getty Images

American League

Leading contenders: Tarik Skubal, Detroit Tigers (146 AXE) vs. Garrett Crochet, Boston Red Sox (139)

Next eight: 3. Hunter Brown, Astros (135); 4. Nathan Eovaldi, Rangers (128); 5. Trevor Rogers, Baltimore Orioles (127); 6. (tie) Framber Valdez, Astros, Joe Ryan, Twins (125); 8. (tie) Max Fried, Yankees, Aroldis Chapman, Red Sox (123); 10. (tie) Michael Wacha, Royals, Drew Rasmussen, Tampa Bay Rays (122)

ESPN BET top two: Skubal (-4000, 97.6% chance of winning), Crochet (+1600)

Sizing up the race: This race remains alive, according to AXE, though Skubal has the edge in all of the bottom-line metrics. The betting markets are a little more emphatic, and those reflect an anticipation of how things will play out from here.

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Both ace lefties have seemingly picked up momentum as the season has progressed. Over the past month, Crochet is 2-0 with a 3.00 ERA and a ridiculous K-to-BB ratio of 40-to-2 over 33 innings. And yet he has gained no ground on Skubal, who is 2-1 with a 1.04 ERA over the same time frame with a more human 35-to-7 ratio.

The two leading versions of WAR can be maddeningly inconsistent on the pitching side, but both systems give Skubal more than a full-win advantage over Crochet. Crochet does hold a narrow advantage in win probability added, but Skubal tops the AL in championship probability added.

How it can flip: The race is clearly Skubal’s to lose, but he needs to keep doing what he’s doing, because the margins are close enough for Crochet to overtake him. For both hurlers, every start from here on out is crucial.

Prediction: Skubal should hold on, if only because he has shown zero evidence of slowing down his epic pace. Unless Skubal struggles, there seems to be no opening for Crochet to squeeze through, no matter how well he pitches.

National League

Leading contenders: Paul Skenes, Pittsburgh Pirates (142 AXE) vs. Cristopher Sanchez, Phillies (142)

Next eight: 3. Zack Wheeler, Phillies (131); 4. (tie) Freddy Peralta, Brewers, Yoshinobu Yamamoto, Dodgers (129); 6. (tie) Nick Pivetta, Padres, Ranger Suarez, Phillies (128); 8. Andrew Abbott, Cincinnati Reds (126); 9. Logan Webb, San Francisco Giants (125); 10. (tie) Jesus Luzardo, Phillies, Nick Lodolo, Reds (123)

ESPN BET top two: Skenes (-20000, 99.5% chance of winning), Sanchez (+1600)

Sizing up the race: The betting markets see Skenes as having an almost Ohtani-like grip on this race. The metrics see it as a dead heat. I tend to think the latter is closer to true than the former, but the markets are typically a reliable indicator.

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Both versions of WAR give Skenes a narrow edge over Sanchez. However, the systems are really confusing when stacked up against each other, with both favorites showing around a full win more value at Baseball Reference than at FanGraphs. That’s nothing to Peralta, the hottest pitcher on the list when compared with our past Awards Watch, whose Baseball Reference WAR is two wins higher than at FanGraphs. This is a prime example of how frustrating the disparities between the systems can be when, after all, they profess to measure the same thing, using the same framework, under precisely the same “wins above replacement” label.

Skenes has an edge in win probability added over Sanchez, who ranks third (San Diego reliever Adrian Morejon is second). But since Skenes toils for a last-place team, Sanchez’s league-leading championship probability added total leaves Skenes (ranked 51st in the NL) in the dust.

It isn’t Skenes’ fault that his team stinks, but it’s precisely why I included championship probability in the calculation. It’s designed to be more of a tiebreaker than anything. If the overall value produced by two players is similar, it seems logical to consider the contexts in which they put up that value.

So, are the overall performances close? Yes, very. Skenes’ sub-2.00 ERA is eye-catching and is likely the number that tags him as the favorite. But his edge in FIP (2.42 to 2.59) is narrow, which explains why he and Sanchez are close in WAR. Their volumes are similar.

How it can flip: It’s a tough call, and if both pitchers should falter down the stretch, Peralta still has a chance to sneak in. But they’d have to struggle because volume (i.e., innings pitched) is a huge factor in today’s pitching environment. Skenes and Sanchez have separated themselves in terms of combining quantity and quality.

Prediction: We probably shouldn’t overthink it. Skenes is the NL’s best pitcher, which isn’t always the same thing as “most deserving Cy Young candidate,” but in this case the two descriptions line up well. The Pirates haven’t backed Skenes off his usual workload, so if he makes the rest of his starts and keeps that ERA under 2.00, Sanchez faces an uphill battle.

Rookie of the Year

Scott Marshall/Getty Images

American League

Leading contenders: Nick Kurtz, Athletics (127 AXE) vs. Roman Anthony, Red Sox (117)

Next eight: 3. Jacob Wilson, Athletics (116); 4. (tie) Noah Cameron, Royals, Carlos Narvaez, Red Sox (113); 6. Colson Montgomery, Chicago White Sox (111); 7. Kyle Teel, White Sox (109); 8. Luke Keaschall, Twins (108); 9. Mike Vasil, White Sox (107); 10. (tie) Jack Leiter, Rangers, Will Warren, Yankees, Shane Smith, White Sox

ESPN BET top two: Kurtz (-50000, 99.8% chance of winning), Anthony (+4000)

Sizing up the race: Anthony is listed above as a leading contender for display purposes only, because this race is over. Kurtz was a heavy favorite already, but the oblique injury that is expected to sideline Anthony for the rest of the regular season sealed the deal. As Klingon Commander Kor said to Captain James T. Kirk, “It would have been glorious.”

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You can’t really win a season award in baseball because of one game. But in Kurtz’s case, his four-homer game against Houston on July 25, in which he had six hits, scored six runs and tied the single-game total base record, comes pretty close. At the very least, it puts his name at the forefront in the minds of voters looking at this season’s rookie class.

At this point, Kurtz’s race is against history. His 1.021 OPS ranks as the fifth best among AL or NL rookies since 1900. The list is topped by Judge’s 1.049 in 2017. Kurtz would have to get blistering hot from here, but it’s not impossible. In terms of OPS+, Kurtz’s 177 currently tops them all, with Jose Abreu’s 173 in 2014 the current end-of-season mark.

You can do this all day, but just a little more: Kurtz’s per-162-game line is currently .301/.397/.624 with 47 homers, 118 RBIs and 123 runs. The dude is 22 years old.

How it can flip: The universe is a complex, unpredictable thing, but at the moment, it’s hard to see any scenario that doesn’t end with Kurtz becoming the Athletics’ ninth Rookie of the Year and first since Andrew Bailey in 2009.

Prediction: Kurtz in a unanimous vote.

National League

Leading contenders: Isaac Collins, Brewers (115 AXE) vs. Drake Baldwin, Atlanta Braves (113)

Next eight: 3. Caleb Durbin, Brewers (111); 4. (tie) Cade Horton, Cubs, Jakob Marsee, Miami Marlins (110); 6. Chad Patrick, Brewers (109); 7. (tie) Braxton Ashcraft, Pirates, Matt Shaw, Cubs, Jack Dreyer, Dodgers (107); 10. (tie) Hurston Waldrep, Braves, Nolan McLean, Mets (106)

ESPN BET top three: Horton (-115, 54% chance of winning), Baldwin (+125), Collins (+600)

Sizing up the race: The markets recently bumped Horton up into favorite’s status but don’t seem to be very convicted about it. The markets aren’t wrong; this race has been a hodgepodge all season. Last time, I drolly suggested the award just go to the Milwaukee Brewers. It’s not entirely a joke. I track team WAR from rookies using a consensus between Baseball Reference and FanGraphs. Here’s the leaderboard:

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1. White Sox (11.55 rookie WAR)
2. Brewers (7.61)
3. Red Sox (5.65)
4. Athletics (5.50)
5. Braves (4.11)

The White Sox have wisely gone all-in with deploying rookies in this rebuilding season, but the Brewers are the best team in baseball. Three Brewers rookies are in the above top 10, and the electric Jacob Misiorowski isn’t far off the pace. (Incidentally, on a recent trip to Milwaukee, I learned that Misiorowski’s family dog is named after Kevin Bacon, which merits extra credit.)

All of this is to avoid the topic at hand, because I really don’t know who should win this race. But I do think that Collins, as the leading representative of the NL’s top rookie class, is deserving for now. But now is a fleeting concept, and Horton is the hottest two-times-through-the-order pitcher on the planet.

Also, you’ll notice that McLean’s 4-1, 1.42 ERA start to his career has already pushed him into the top 10. He probably can’t win?

How it can flip: The markets have picked up on how hot Horton is, and if all current trends continue (which they of course will not), he’ll probably win. Over his past nine outings, Horton is 6-1 with a 0.77 ERA.

Prediction: Horton has allowed less than a run every other start since the All-Star break. If he maintains anything close to that pace, he’ll win. Otherwise, give it to a Brewer.

Manager of the Year

Nick Cammett/Diamond Images via Getty Images

American League

Leading contenders: A.J. Hinch, Tigers (108.3 EARL) vs. John Schneider, Blue Jays (107.8)

Next three: 3. Joe Espada, Astros (107.0); 4. Warren Schaeffer/Ron Washington, Los Angeles Angels (106.3); 5. Stephen Vogt, Guardians (105.2)

Breaking News from Jeff Passan

Download the ESPN app and enable Jeff Passan’s news alerts to receive push notifications for the latest updates first. Opt in by tapping the alerts bell in the top right corner. For more information, click here.

Sizing up the race: ESPN BET doesn’t help us with the manager races, but these standings make sense. It truly feels like a coin flip between Hinch and Schneider at this point.

How it can flip: EARL gives Hinch the razor-thin edge, but it probably comes down to which team lands the top overall seed in the AL bracket. Thus, the end of the season will determine this race. For what it’s worth, Hinch’s club has a hammerlock on the AL Central title, while Schneider’s Blue Jays have plenty of work to do in holding off the Yankees and Red Sox.

Prediction: Hinch’s Tigers will land that top seed and give him the leg up in the awards balloting. It would be his first Manager of the Year Award after five previous top-five finishes in the balloting.

National League

Leading contenders: Pat Murphy, Brewers (113.7 EARL) vs. Clayton McCullough, Marlins (106.9)

Next three: 3. Oliver Marmol, St. Louis Cardinals (106.1); 4. Rob Thomson, Phillies (103.9); 5. Craig Counsell, Cubs (103.4)

Sizing up the race: Murphy is going to win his second straight NL Manager of the Year Award. Everything works in his favor. The Brewers have thumped their preseason projections and are likely to enter the playoffs as the top overall seed. They are 26-17 in one-run games. They have all those rookies. And they play a team-oriented style built on contributions from a number of unsung role players.

Among the others, Counsell is most likely to finish second. McCullough has a tiny edge by EARL, but the Marlins’ recent pitching collapse has his trajectory arrow pointed downward.

How it can flip: The only way for this outlook to change is a Brewers collapse paired with an epic Cubs finish that allows Chicago to overcome its huge NL Central deficit and win the division. Otherwise, Murphy will once again outshine the guy he coached at Notre Dame and with whom he later worked as the bench coach in Milwaukee.

Prediction: A Murph runaway.



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25 under 25: Ranking the WNBA's best young players
Esports

25 under 25: Ranking the WNBA’s best young players

by admin August 29, 2025



Aug 27, 2025, 07:30 AM ET

An influx of young talent is helping to transform the WNBA. Rookie All-Stars Caitlin Clark and Angel Reese made an immediate impact last season, and 2025’s first-year players have followed suit. Paige Bueckers, Sonia Citron and Kiki Iriafen were named All-Stars this summer, while No. 2 pick Dominique Malonga has been setting WNBA production records as a teenager.

The six All-Stars younger than age 25 this year are the most since 2011, and the 2024 (two) and 2025 drafts (three) have already produced as many or more All-Stars as the total between 2021 and 2023 (Aliyah Boston and Rhyne Howard).

Ranking these young players required making some hard calls, particularly at the top, where Boston, Bueckers and Clark have all shown MVP potential. We’ve put them in order based on their expected peak value rather than current production — meaning Malonga, the league’s youngest player at age 19, gets extra credit for her upside relative to players whose performances are more consistent right now.

To be eligible for ESPN’s 25 under 25, players must have played in the WNBA already, so stashed draft picks such as Juste Jocyte — taken No. 5 by the Golden State Valkyries with their first rookie draft pick — aren’t eligible.

With that in mind, let’s run down the brightest young talent in the WNBA.

Due to injuries, she has been limited to 13 games this season, averaging 16.5 points, 8.8 assists and 5.0 rebounds. But when healthy, Clark’s impact is enormous: She stretches the floor with her shooting range, pushes the pace and picks defenses apart with her passing. The 23-year-old brings an unmatched excitement factor every time she’s on court, and her confidence spreads to the whole team. She is also the biggest draw on the road of any WNBA player, so her effect on the entire league is huge. — Michael Voepel

Expectations were high for Bueckers entering the pros, with one GM telling ESPN, “She’ll be a Hall of Famer.” In Year 1, she has largely lived up to the hype and is on pace to join Clark as the only players to average 19 points and 5 assists in their rookie season.

Bueckers’ efficiency has mostly carried over from UConn, with her 46.6% field goal shooting the best of any guard averaging at least 16 points in the league. She has shown the midrange game still has a place in modern basketball, even in 2025. Her crowning achievement came last week when she became the first player to drop 40-plus points in a game on 80% efficiency. — Alexa Philippou

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3. Aliyah Boston, Indiana Fever, C/F, 6-5

The Fever began their rebuild well before Clark arrived in Indianapolis. The 2024 No. 1 pick, Boston is just as crucial to the Fever’s success as Clark and has been a major factor in keeping the team afloat this season as it navigates injuries.

Boston is averaging a career-best 15.2 points — fourth best among players under 25 — and shooting an efficient 54.6% from the floor, third best in the same group. She has a franchise-record 15 double-doubles this season, fourth most in the league. Boston’s facilitating has always been a strength, especially in tandem with Clark.

And Boston can still level up. Her rookie year was focused on playing in the post. Last season was about evolving the pick-and-roll with Clark. During the offseason, Boston focused on conditioning, and this summer she has become a bigger part of the offense. Next up is taking more 3s and becoming more of a three-level scoring threat and floor spreader. — Kendra Andrews

There are no regrets about the Storm passing on a pair of rookie All-Stars to take Malonga. Growing over the course of her first season in the United States, the No. 2 pick has blossomed in August, averaging 13.5 PPG and 7.4 RPG on 60% shooting. Malonga’s athleticism allows her to make plays no other player her size can make, and she also displays incredible touch as a shooter.

Given Malonga would be entering her second college season if she were American, she has years of development ahead. That gives Malonga, whose three 20-point games are the most ever by a WNBA teenager, MVP potential. — Kevin Pelton

After shattering rebounding records as a rookie, the biggest question surrounding Reese was how she could evolve and grow in her sophomore year. She spent much of the Unrivaled season working on her shooting, and it shows: Her scoring and efficiency have improved this season in the W.

But Reese’s biggest offensive jump has come in her playmaking. She’s averaging 3.7 assists per game, top 5 among all forwards and the most among WNBA players under the age of 25. She excels at passing in the post, a nod to her chemistry with Kamilla Cardoso, and better understands how her presence down low opens up her teammates more.

On defense, her rebounding is as good as ever. She leads the league at 12.2 boards per game, and just 25 games in has already tied her rookie record as the fastest player in WNBA history to reach 300 rebounds in a single season. — Andrews

The No. 3 pick of this year’s draft has blown away expectations for her rookie season, emerging as Washington’s go-to scorer after the Brittney Sykes trade, as well as a legitimate perimeter stopper. More of a role player alongside the Notre Dame backcourt of Hannah Hidalgo and Olivia Miles, Citron is averaging more points (15.2) in the W than she did as a college senior (14.1) but has maintained her efficiency, shooting 42% on 3s and 88% from the line. Citron’s .608 true shooting percentage ranks in the WNBA’s top 10. And at 21, she’s younger than the typical college product. — Pelton

The No. 3 pick in the 2024 draft, Cardoso has improved her stats from her rookie season across the board, averaging 13.4 points, 8.4 rebounds and 2.3 assists. The 9-28 Sky have struggled and will miss the playoffs for the second year in a row. But at 24, Cardoso has shown the kind of progress a young post player needs, which bodes well for a long career. — Voepel

Onlookers were calling Jackson pro-ready since her days at Tennessee, and since arriving as the No. 4 pick in 2024, she has shown why. She can be a matchup nightmare for opposing defenders and at her best is a prolific bucket getter and stellar shot creator, already boasting eight 20-plus point games for the Sparks since mid-June. The more efficient and consistent she can be offensively, and if she can stay steady on defense, the more Jackson will further establish herself as one of the best young talents in the game. — Philippou

9. Cameron Brink, Los Angeles Sparks, F, 6-4

Brink was one of the more difficult players for our panel to assess given she has played in only 26 games over two years and is still making her way back to full form following a June 2024 ACL tear. But it was easy to see why she went No. 2 in the 2024 draft, particularly shining on the defensive end as an elite rim protector. While she’s still getting her feet back under her after returning to the floor in late July, her 3-point shooting (20-for-44, 45.5%) has excelled, a good sign for her offensive development. — Philippou

10. Kiki Iriafen, Washington Mystics, F, 6-3

The No. 4 draft pick in April, Iriafen turned 22 this week. She was an All-Star after showing how quickly she adapted to the pro game, especially her ability to rebound at an elite level. She is averaging 12.9 points and 8.7 rebounds and has started every game for Washington. She and rookie teammate Sonia Citron look to be the key factors for the Mystics in rebuilding. — Voepel

Lacan was the Sun’s 2024 first-round pick though she didn’t debut in the WNBA until this July. But 20 games in, she has been worth the wait. The 21-year-old Frenchwoman boasts an astounding plus-20.3 net rating for the Sun, and her two-way impact has revitalized a team that had just two wins prior to her arrival. (The Sun have won seven games since.) Her defensive prowess has translated immediately — her 2.4 steals per game are tied for the most in the league — and she’s a standout facilitator, already recording a 14-assist, 0-turnover game earlier this month. — Philippou

12. Saniya Rivers, Connecticut Sun, G, 6-1

The Sun have had a rocky year, but it’s easy to see the promise of their young core, including this 2025 first-rounder. The former NC State standout and No. 8 pick has established herself as a stellar defender (1.6 SPG, 0.9 BPG) with the potential to be a perennial All-Defensive Team selection. Her offensive game (8.3 PPG, 41.4% FG, 32.3 3FG%) has room for growth, but she has shown bright spots with her facilitating (including a handful of games with six or more assists) and scoring that the Sun can build off of. — Philippou

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Akoa Makani moved from Cameroon to France as a child and has played professionally there for several years. At 24, she made her WNBA debut this season and started 32 games as a key part of the new-look Mercury. Most WNBA fans didn’t know much about Akoa Makani but have watched as she has adjusted well to the league. She is averaging 8.4 points, 2.6 assists and 2.2 rebounds. — Voepel

When we last saw Horston in the WNBA — she tore her ACL during Athletes Unlimited play in April which has sidelined her this season — she had received votes for both Most Improved Player and Sixth Player in 2024. After playing heavily at power forward as a rookie in 2023, the versatile Horston shifted to the wing and shot 57% on her 2s. The Seattle bench has missed that punch, plus Horston’s ability to rack up steals and blocks. Whether she can improve on a 25% career 3-point shooting will define Horston’s upside. — Pelton

Andrea Cardani/NBAE via Getty Images

After averaging less than four points in her first two WNBA seasons with Las Vegas and Atlanta, Rupert is scoring 9.0 points per game on 46.3% 3-point shooting — the third-best mark among players under 25 — which gives the Valkyries a big body to stretch the floor. Part of her growth has come from more playing time with Golden State. But she also developed her finishing ability around the rim with the French national team for the 2024 Olympics. — Andrews

Paopao’s slide to the second round of this year’s draft has paid off for the Dream, who have plugged her into their guard rotation after trading away their first-round pick. A national champion at South Carolina in 2024, Paopao has contributed to Atlanta’s rise in the standings by shooting 42% from 3-point range. Only Citron has been more accurate among rookies this season. — Pelton

17. Janelle Salaun, Golden State Valkyries, F, 6-2

Salaun is another player whose impact and potential can be better measured by looking at her career overseas. In the 2024-25 season with Famila Schio in Italy, she helped the team win the domestic cup and the league championship and was named Finals MVP, averaging 13.2 points, 5.4 rebounds and 1.2 steals over the five-game series for the league championship. With the Valkyries, she has been a staple in the starting lineup and a reliable scorer. Her dependability and availability have been two of her strongest attributes; aside from the three games she missed competing in EuroBasket, she has appeared in every WNBA contest this season and suited up for all 30 games with Famila Schio. — Andrews

18. Aneesah Morrow, Connecticut Sun, F, 6-1

She averaged a double-double (20.5 PPG, 12.3 RPG) in college, spending two years at DePaul and two at LSU. Undersized in the WNBA, she is now adjusting her skill set. Still, Morrow has started 16 games for the Sun and is averaging 7.5 points and 6.4 rebounds. Look for the 22-year-old to improve her perimeter shooting — she is at 26.7% from 3-point range — as she progresses as a pro. — Voepel

Edwards got buried in the rotation in Washington, but she had enough moments in her rookie season that should make the Sun excited about her potential. She averaged 7.6 points and 5.6 rebounds in 21.8 minutes and started 17 of 34 contests last year. Her averages are down this season, but she remains incredibly efficient. Playing time and usage haven’t boomed since her arrival in Connecticut, but it’s easy to believe she has more growth in her, given time and opportunity. — Andrews

Miller is another tricky player to assess since she hasn’t yet found a steady role in the league. She was drafted No. 2 in 2023, highly regarded for her athleticism and versatility, and averaged 12.1 points as a rookie with Minnesota. But she saw minimal time there the past two seasons, after being hampered by injuries and falling out of the rotation. After being traded last month, she has the opportunity to regain her footing in Dallas and brings a different look to the wing with her size compared to several of her undersized teammates. — Philippou

21. Aziaha James, Dallas Wings, G, 5-9

A fixture in the Wings’ rotation in July, James averaged 9.4 PPG to rank sixth among rookies that month. James has faded in August, in part because she has shot 28% from the 3-point line. A 34% 3-point shooter during her last two seasons at NC State, James has room for improvement. That and her superior size give her the nod over fellow Dallas rookie JJ Quinerly, whose season ended this week because of an ACL sprain. — Pelton

22. Carla Leite, Golden State Valkyries, G, 5-9

Leite averages just 7.3 points for the Valkyries, playing 17.8 minutes off the bench, but her play in Europe suggests she has a much higher offensive ceiling. This year she was named Finals MVP after leading French club Villeneuve d’Ascq to a EuroCup championship in April, averaging 20.5 points, 6.0 assists and 2.5 rebounds. — Andrews

23. Awak Kuier, Dallas Wings, F, 6-6

The No. 2 pick in 2021 has yet to make a big impression stateside, averaging 2.6 PPG in three seasons in Dallas. Since last appearing for the Wings in 2023 at age 22, however, Kuier has shown dramatic development in Europe. Kuier averaged 16.8 PPG and 6.3 RPG for Umana Reyer Venezia in EuroLeague play last year, ranking third in scoring behind WNBA All-Stars Brionna Jones and Emma Meesseman. — Pelton

She was the 19th pick in April out of Florida State and has been a good fit as a reserve for the injury-plagued Fever. Timpson has another former Seminoles star, Fever veteran forward Natasha Howard, to learn from. Timpson, 22, is averaging 2.7 points and 2.1 rebounds. Her playing time has fluctuated a lot, but she has shown promising moments. It will be a big offseason for her to grow her game. — Voepel

25. Laeticia Amihere, Golden State Valkyries, F, 6-3

After being drafted No. 8 in 2023 by Atlanta, Amihere has found a home with Golden State. She had her first stint with the team during training camp, where she averaged 12.5 points on 60% shooting in 17.4 minutes. She was waived but rejoined the team in June and has been a steady role player since. — Andrews



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GameFi Guides

AI Just Helped Make Old Cells Young Again

by admin August 23, 2025



In brief

  • OpenAI built GPT-4b micro, a downsized model specialized for protein engineering, in collaboration with longevity startup Retro Biosciences.
  • The model designed new variants of the Yamanaka factors, proteins used to reprogram adult cells into stem cells, achieving 50-fold higher efficiency in lab tests.
  • Researchers say the results show how AI could accelerate life sciences and longevity research, though the work remains early and lab-based.

AI isn’t just cranking out code, images, and songs anymore. Now it can redesign the proteins inside your cells.

On a company blog post, OpenAI just announced that it collaborated with Retro Biosciences, a Silicon Valley longevity startup, to train a specialized model called GPT-4b micro. Unlike the chatbots you know, this model wasn’t fine-tuned for banter or brainstorming. Instead, it was trained on protein sequences, biological text, and 3D structure data so it could propose entirely new variants of proteins used in regenerative medicine.

The results were surprising: GPT-4b micro successfully re-engineered two of the famous Yamanaka factors—proteins that won a Nobel Prize for their ability to turn adult cells back into stem cells. Stem cells are special cells that can both self-renew (regenerate) and differentiate into many other cell types in the body. They’re important because they act as the body’s repair system and hold huge potential for treating diseases, regenerating tissues, and even reversing aspects of aging.

In the lab, the AI-designed versions showed 50-fold higher expression of stem cell markers and repaired DNA damage more effectively than the originals. In other words, they made old cells act younger, faster.

Why this matters

The Yamanaka factors are central to regenerative medicine, with potential to treat blindness, diabetes, organ failure, and more. But in practice, they’re inefficient—less than 0.1% of cells usually convert to stem cells, and the process can take weeks. By finding variants that dramatically boost efficiency, AI could accelerate cell reprogramming research by years, cutting down the trial-and-error of conventional biotech.

This could ripple outward:

  • Longevity startups could use AI-designed proteins to rejuvenate cells more safely and consistently.

  • Drug development timelines could shrink if models like GPT-4b micro become protein engineers on demand.

  • Synthetic biology might move past “what evolution gave us” and start exploring huge design spaces that were once impossible for humans to navigate.

But also: big caveats

The science is early, and OpenAI admits this is a proof-of-concept. Lab validation is one thing; moving into clinical therapies is another. Protein engineering is notorious for failing in translation from dish to organism, let alone into people.

There are also biosecurity worries—if AI can rapidly design powerful proteins, then that power cuts both ways. OpenAI’s answer is transparency: The work with Retro is being openly published so others can replicate and critique it.



For OpenAI, this isn’t just about one experiment; it’s about showing that language-model tooling can be redirected toward scientific discovery.

“When researchers bring deep domain insight to our models, problems that once took years can shift in days,” said Boris Power, who leads research partnerships at the company.

If that’s true, then AI won’t just change how we write or code—it could start changing what it means to age, heal, and stay alive.

Generally Intelligent Newsletter

A weekly AI journey narrated by Gen, a generative AI model.



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August 23, 2025 0 comments
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