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Cells

A few hours into The Rogue Prince of Persia's 1.0 release, it's Dead Cells with beautifully balletic carnage - but hopefully there's a bit more to it
Game Reviews

A few hours into The Rogue Prince of Persia’s 1.0 release, it’s Dead Cells with beautifully balletic carnage – but hopefully there’s a bit more to it

by admin August 23, 2025



Our pal the Prince of Persia has been through a lot since his seminal debut in 1989, his form ever-shifting like, well, the sands of time. But throughout it all, from his eye-popping rotoscoped origins to his leap into the third dimension, and then, over the last few years, back into the side-on world again, there’s one thing that’s consistently defined the series’ core: movement. Sure, old Prince was positively plodding compared to his later incarnations, but a sense of unparalleled fluidity has stayed true. I say all this, because The Rogue Prince of Persia, which has just had its 1.0 release on PC, Xbox, PlayStation, PlayStation Plus, and Game Pass after a year in Steam early access, still manages to feel like part of the series’ nearly four-decade legacy, despite yet another reimagining of its form.


It’s admittedly still early days for me as far as The Rogue Prince of Persia goes, and I’ve only had a couple of hours with it right now – but already I’m impressed with how chef’s kiss its movement feels. Before we get too deep into that, though, it’s worth taking a step back. The Rogue Prince of Persia, if you didn’t already know, comes from Evil Empire, the studio responsible for the acclaimed Dead Cells’ long tail of post-launch support before original developer Motion Twin pulled the plug. And there’s unquestionably a lot of the old in Evil Empire’s new.


The Rogue Prince of Persia might swap Dead Cell’s dark, dank fantasy aesthetic for the shimmering domes and arid vistas of the titular city – here, you’re attempting to overthrow Nogai the Hun and his invading army – but at its core, it’s still a combat-heavy side-scroller featuring labyrinthine procedurally assembled levels, persistent power-ups, temporary per-run weapons and buffs, and, yes, a roguelike structure. You fight, you die, you go again, slowly gaining news skills and upgrades in the hope that next time, this time, will be the one. It’s certainly not a carbon copy, but it’s familiar enough – right down to specifics like its fast-travel interface – that it’s been hard to shake the feeling that, as a Dead Cells fan, I’ve already danced this particular dance a few too many times before.

The Rogue Prince of Persia release trailer.Watch on YouTube


Exactly how much that matters, though, I’m not yet entirely sure. And mainly that’s down to movement. As is befitting of the series’ legacy, The Rogue Prince of Persia feels fantastic from the off, with a sense of fluidity to the Prince’s parkour-inspired moveset that’s bordering on the sublime. He’s a nimble one; slickly switching from leaps to lunges to wall runs to pole jumps with fleet-footed abandon, and all with the press of a couple of intuitively arranged buttons. And it’s fast. There’s a rhythm to the traversal-skewed action, as you sprint, drop, squat, pounce, slash, and vault over enemies, that – after a bit of initial adjustment – is enormously rewarding. And shrewedly, actually rewarding, given that perfectly timed acrobatics further increase your nimbleness across the world.


That gratifying sense of movement extends to combat too, with melee and ranged attacks managing to feel as punchy and crunchy as the Prince is quick. And the way all those traversal tricks cleverly fold into combat encounters helps give The Rogue Prince of Persia a vibe of its own. All of this, I should note, is wrapped up in some fantastic presentation. It’s gorgeously animated for starters – little moments like the Prince hurling himself backward into each level’s fast-travel wells adds bags of personality to the experience – and the varied biomes look beautiful too. The whole thing’s fashioned from a mix of 3D foregrounds and 2D backdrops seamlessly brought together by a visual style reminiscent of famed comic book artist Moebius. And while you could perhaps argue the game’s original art – with its strikingly purple Prince – was a little more characterful before its mid-development do-over, it’s still a looker.


So a few hours in, my thoughts are mixed. There’s a sense Evil Empire could perhaps have stepped further out of Dead Cells’ shadow, because there’s an underlying familiarity to The Rogue Prince of Persia that’s dulling my enthusiasm a little. My hope, though, is it’ll eventually start to open out into something a little bolder. But for now at least, that movement – that beautiful balletic carnage – is carrying me through.



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August 23, 2025 0 comments
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GameFi Guides

AI Just Helped Make Old Cells Young Again

by admin August 23, 2025



In brief

  • OpenAI built GPT-4b micro, a downsized model specialized for protein engineering, in collaboration with longevity startup Retro Biosciences.
  • The model designed new variants of the Yamanaka factors, proteins used to reprogram adult cells into stem cells, achieving 50-fold higher efficiency in lab tests.
  • Researchers say the results show how AI could accelerate life sciences and longevity research, though the work remains early and lab-based.

AI isn’t just cranking out code, images, and songs anymore. Now it can redesign the proteins inside your cells.

On a company blog post, OpenAI just announced that it collaborated with Retro Biosciences, a Silicon Valley longevity startup, to train a specialized model called GPT-4b micro. Unlike the chatbots you know, this model wasn’t fine-tuned for banter or brainstorming. Instead, it was trained on protein sequences, biological text, and 3D structure data so it could propose entirely new variants of proteins used in regenerative medicine.

The results were surprising: GPT-4b micro successfully re-engineered two of the famous Yamanaka factors—proteins that won a Nobel Prize for their ability to turn adult cells back into stem cells. Stem cells are special cells that can both self-renew (regenerate) and differentiate into many other cell types in the body. They’re important because they act as the body’s repair system and hold huge potential for treating diseases, regenerating tissues, and even reversing aspects of aging.

In the lab, the AI-designed versions showed 50-fold higher expression of stem cell markers and repaired DNA damage more effectively than the originals. In other words, they made old cells act younger, faster.

Why this matters

The Yamanaka factors are central to regenerative medicine, with potential to treat blindness, diabetes, organ failure, and more. But in practice, they’re inefficient—less than 0.1% of cells usually convert to stem cells, and the process can take weeks. By finding variants that dramatically boost efficiency, AI could accelerate cell reprogramming research by years, cutting down the trial-and-error of conventional biotech.

This could ripple outward:

  • Longevity startups could use AI-designed proteins to rejuvenate cells more safely and consistently.

  • Drug development timelines could shrink if models like GPT-4b micro become protein engineers on demand.

  • Synthetic biology might move past “what evolution gave us” and start exploring huge design spaces that were once impossible for humans to navigate.

But also: big caveats

The science is early, and OpenAI admits this is a proof-of-concept. Lab validation is one thing; moving into clinical therapies is another. Protein engineering is notorious for failing in translation from dish to organism, let alone into people.

There are also biosecurity worries—if AI can rapidly design powerful proteins, then that power cuts both ways. OpenAI’s answer is transparency: The work with Retro is being openly published so others can replicate and critique it.



For OpenAI, this isn’t just about one experiment; it’s about showing that language-model tooling can be redirected toward scientific discovery.

“When researchers bring deep domain insight to our models, problems that once took years can shift in days,” said Boris Power, who leads research partnerships at the company.

If that’s true, then AI won’t just change how we write or code—it could start changing what it means to age, heal, and stay alive.

Generally Intelligent Newsletter

A weekly AI journey narrated by Gen, a generative AI model.



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August 23, 2025 0 comments
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